Lung Kruppel-like Factor, a Zinc Finger Transcription Factor, Is Essential for Normal Lung Development
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چکیده
منابع مشابه
Transcription factor zinc finger and BTB domain 1 is essential for lymphocyte development.
Absent T lymphocytes were unexpectedly found in homozygotes of a transgenic mouse from an unrelated project. T cell development did not progress beyond double-negative stage 1 thymocytes, resulting in a hypocellular, vestigial thymus. B cells were present, but NK cell number and B cell isotype switching were reduced. Transplantation of wild-type hematopoietic cells corrected the defect, which w...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1999
ISSN: 0021-9258
DOI: 10.1074/jbc.274.30.21180